Preparation and Evaluation of Nanofibrous Hydroxypropyl Cellulose and β-Cyclodextrin Polyurethane Composite Mats

A series of nanofibrous composite mats based on polyurethane urea siloxane (PUUS), hydroxypropyl cellulose (HPC) and β-cyclodextrin (β-CD) was prepared using electrospinning technique. PUUS was synthesized by two steps solution polymerization procedure from polytetramethylene ether glycol (PTMEG), dimethylol propionic acid (DMPA), 4,4'-diphenylmethane diisocyanate (MDI) and 1,3-bis-(3-aminopropyl) tetramethyldisiloxane (BATD) as chain extender. Then, the composites were prepared by blending PUUS with HPC or βCD in a ratio of 9:1 (w/w), in 15% dimethylformamide (DMF). The PUUS and PUUS based composite solutions were used for preparation of nanofibrous mats. In order to identify the potential applications, different techniques were used to evaluate the chemical structure (Fourier transform infrared-attenuated total reflectance spectroscopy-FTIR-ATR), morphological structure (Scanning electron microscopy-SEM and Atomic force microscopy-AFM), surface properties (contact angle, dynamic vapors sorption-DVS), mechanical characteristics (tensile tests), thermal (differential scanning calorimetry-DSC) and some preliminary tests for biocompatibility and microbial adhesion.