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Postmastectomy low-grade angiosarcoma. An unusual case clinically resembling a lymphangioma circumscriptum
D Drachman1, L Rosen, D Sharaf
1Department of Dermatology, Mount Sinai Medical Center of Greater Miami, Miami Beach, Florida.
The American Journal of Dermatopathology
|June 1, 1988
Summary
A rare cutaneous angiosarcoma developed in a lymphedematous limb 15 years post-mastectomy. This slow-growing cancer presented like lymphangioma circumscriptum, showing a remarkably benign clinical course.
Area of Science:
- Oncology
- Dermatology
- Pathology
Background:
- Cutaneous angiosarcoma is a rare malignancy of blood vessels.
- Chronic lymphedema can be a risk factor for secondary malignancies.
- Post-mastectomy lymphedema presents a unique clinical challenge.
Observation:
- A 90-year-old woman presented with a skin neoplasm on a chronically lymphedematous leg.
- The lesion appeared clinically similar to lymphangioma circumscriptum.
- The patient had a history of radical mastectomy for breast cancer 15 years prior.
Findings:
- Histopathological examination confirmed a low-grade cutaneous angiosarcoma.
- The angiosarcoma exhibited an unusually benign clinical behavior.
- A 3-year follow-up revealed no signs of aggressive progression.
Implications:
- This case highlights a rare presentation of angiosarcoma in the context of chronic lymphedema.
- The findings suggest that some angiosarcomas may follow an indolent course.
- Further research is needed to understand the specific risk factors and behavior of angiosarcoma in lymphedematous tissues.