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Updated: Dec 23, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding

Jing Yu1,2,3, Luis E Gimenez4, Ciria C Hernandez4

  • 1iHuman Institute, ShanghaiTech University, Pudong, Shanghai 201210, China.

Science (New York, N.Y.)
|April 25, 2020
PubMed

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