Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Neutrophil Extracellular Traps on Clinical Outcome after Subarachnoid Hemorrhage: A Translational Narrative Review.

Translational stroke research·2026
Same author

A cross-sectional analysis of multidimensional clinical profiles of older adults engaged in structured post-ICU follow-up: age is not the whole story.

European geriatric medicine·2026
Same author

LIFE-UP Day audit to monitor implementation of post-intensive care syndrome prevention practices: a multicentre cross-sectional study in Belgian intensive care units.

BMJ open·2026
Same author

Authors reply: "Evolution of triglyceride and total cholesterol levels after critical illness: Preliminary insights into post-ICU metabolic sequelae".

Journal of critical care·2026
Same author

Evolution of triglyceride and total cholesterol levels after critical illness: Preliminary insights into post-ICU metabolic sequelae.

Journal of critical care·2026
Same author

Quantifying the recollection of discomfort and emotional suffering during a stay in intensive care: development and validation of the EXPRIM questionnaire : EXPRIM: quantification of discomfort experienced during an ICU stay.

Journal of patient-reported outcomes·2026
Same journal

Correction to "Mathematical Modelling of COVID-19 Transmission in Kenya: A Model with Reinfection Transmission Mechanism".

Computational and mathematical methods in medicine·2025
Same journal

RETRACTION: Ligustrazine Inhibits Lung Phosphodiesterase Activity in a Rat Model of Allergic Asthma.

Computational and mathematical methods in medicine·2025
Same journal

RETRACTION: Delivery of miR-224-5p by Exosomes from Cancer-Associated Fibroblasts Potentiates Progression of Clear Cell Renal Cell Carcinoma.

Computational and mathematical methods in medicine·2025
Same journal

RETRACTION: Empirical Analysis of the Nursing Effect of Intelligent Medical Internet of Things in Postoperative Osteoarthritis.

Computational and mathematical methods in medicine·2025
Same journal

RETRACTION: Evaluation and Analysis of the Intervention Effect of Systematic Parent Training Based on Computational Intelligence on Child Autism.

Computational and mathematical methods in medicine·2024
Same journal

RETRACTION: Humanistic Spirit Training of Medical Students Based on Multisource Medical Data Fusion.

Computational and mathematical methods in medicine·2024
See all related articles

Related Experiment Video

Updated: Dec 23, 2025

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
07:11

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

9.5K

Model-Based Weaning Tests for VA-ECLS Therapy.

Simon Habran1, Thomas Desaive1, Philippe Morimont1

  • 1University of Liège, GIGA-In Silico Medicine, Belgium.

Computational and Mathematical Methods in Medicine
|April 25, 2020
PubMed
Summary
This summary is machine-generated.

A patient-specific model of cardiovascular systems and venoarterial extracorporeal life support (VA-ECLS) was developed. This model shows promise for improving VA-ECLS weaning strategies in intensive care units.

More Related Videos

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software
08:22

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software

Published on: August 31, 2018

6.9K
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

25.3K

Related Experiment Videos

Last Updated: Dec 23, 2025

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
07:11

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

9.5K
A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software
08:22

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software

Published on: August 31, 2018

6.9K
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

25.3K

Area of Science:

  • Cardiovascular Physiology
  • Medical Device Engineering
  • Computational Biology

Background:

  • Venoarterial extracorporeal life support (VA-ECLS) is a critical intervention for severe cardiogenic shock.
  • Weaning patients from VA-ECLS presents significant clinical challenges.
  • A deeper understanding of the cardiovascular system during VA-ECLS is needed to optimize therapy.

Purpose of the Study:

  • To develop a patient-specific computational model of the cardiovascular system coupled with VA-ECLS.
  • To validate the model using experimental data from pig studies.
  • To demonstrate the potential of model-based approaches for improving VA-ECLS weaning strategies.

Main Methods:

  • Construction of a patient-specific cardiovascular model.
  • Integration of the model with a VA-ECLS simulation.
  • Validation of the model against hemodynamic data from pig experiments.

Main Results:

  • The developed model accurately represents the cardiovascular system under VA-ECLS.
  • Simulated hemodynamic quantities showed a mean difference of less than 5% compared to experimental data.
  • The model provides a promising tool for understanding VA-ECLS dynamics.

Conclusions:

  • Patient-specific modeling is a feasible approach to study VA-ECLS.
  • Model-based strategies may enhance the safety and efficacy of VA-ECLS weaning.
  • Further research can leverage this model for clinical decision support in critical care.