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Related Concept Videos

Brain Imaging01:14

Brain Imaging

581
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
581
Bipolar Disorder01:30

Bipolar Disorder

526
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
526
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

466
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
466

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Related Experiment Video

Updated: Dec 23, 2025

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
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Microstructural Alterations in Bipolar and Major Depressive Disorders: A Diffusion Kurtosis Imaging Study.

Daisuke Sawamura1,2, Hisashi Narita3, Naoki Hashimoto3

  • 1Department of Biomarker Imaging Science, Graduate School of Medical Science and Engineering, Hokkaido University, Sapporo, Japan.

Journal of Magnetic Resonance Imaging : JMRI
|April 25, 2020
PubMed
Summary

Diffusion kurtosis imaging (DKI) detects brain microstructural changes in bipolar disorder (BD) and major depressive disorder (MDD). DKI indices can differentiate between BD and MDD and correlate with disease severity and duration.

Failed At:

2026-06-19T13:47:54.302529+00:00

Keywords:
bipolar disorderdiffusion kurtosis imagingmajor depressive disordermean kurtosismicrostructural alterations

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