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Net Effects of NETs: New Concepts
Teruki Dainichi1, Saeko Nakajima1, Masashi Iwata1
1Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Abstract:
It is challenging to investigate neutrophil extracellular traps (NETs) and bacterial colonization in vivo. Bitschar et al. (2020) oppose an existing paradigm regarding neutrophils in host defense and propose that neutrophils increase Staphylococcus aureus skin colonization through NETs, not by trapping microbes but via indirect mechanisms. These results are open to interpretation and should stimulate productive discussions.
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