Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stimulants01:29

Stimulants

754
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
754
Vaporization01:18

Vaporization

37.0K
The physical form of a substance changes by changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. For vaporization to occur, kinetic energy must be greater than the intermolecular forces that keep molecules bonded. The amount of energy needed to vaporize a quantity of liquid at a given pressure and a constant temperature is called the heat of vaporization. When...
37.0K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

177
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
177
Inhaled Medications01:23

Inhaled Medications

632
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
632
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

133
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
133
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

174
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
174

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

After Hours, After Thought? Rethinking CT Stewardship in Pediatric Head Trauma.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes·2026
Same author

Pediatric transfusion camp: Developing, piloting and evaluation of a Canadian national pediatric transfusion medicine curriculum.

Transfusion·2026
Same author

Physicians' and nurses' exposure to child injury and death in emergency departments: implications for vicarious trauma and awareness for injury preventability.

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention·2026
Same author

Evaluating the quality of Canadian pediatric sepsis clinical practice guidelines.

CJEM·2026
Same author

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same author

Just the facts: damage control resuscitation in pediatric trauma.

CJEM·2026

Related Experiment Video

Updated: Dec 23, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
08:39

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies

Published on: August 25, 2018

26.2K

Vaping implications for children and youth.

Meghan Gilley1, Suzanne Beno2

  • 1Division of Pediatrics, Department of Emergency Medicine, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia.

Current Opinion in Pediatrics
|April 26, 2020
PubMed
Summary
This summary is machine-generated.

Adolescent vaping rates are soaring due to aggressive marketing and appealing flavors, leading to significant health issues. Stricter regulations are needed to curb youth access and marketing of e-cigarettes.

More Related Videos

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
10:44

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System

Published on: May 24, 2017

11.9K
A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
09:30

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

8.7K

Related Experiment Videos

Last Updated: Dec 23, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
08:39

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies

Published on: August 25, 2018

26.2K
Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
10:44

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System

Published on: May 24, 2017

11.9K
A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
09:30

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

8.7K

Area of Science:

  • Public Health
  • Adolescent Health
  • Tobacco Control

Background:

  • E-cigarette use is a recent phenomenon with rapidly increasing rates among adolescents.
  • Aggressive marketing, appealing flavors, and attractive designs contribute to youth uptake.
  • Vaping has reversed decades of declining nicotine use among young people.

Purpose of the Study:

  • To review the mechanisms of e-cigarettes.
  • To examine the health implications of e-cigarette use in youth.
  • To explore the epidemiology and regulatory strategies for adolescent vaping.

Main Methods:

  • Literature review of e-cigarette development, marketing, and health consequences.
  • Analysis of epidemiological data on youth vaping prevalence.
  • Examination of current regulatory approaches to e-cigarettes.

Main Results:

  • E-cigarette use has surged among high school students, with 20.8% using them in the past month.
  • Youth vaping has led to increased nicotine addiction and concerning short-term health issues like seizures and lung injury.
  • Industry marketing tactics, including flavors and design, appeal strongly to adolescents, fostering perceived safety.

Conclusions:

  • Epidemic e-cigarette use among youth poses significant short-term and long-term health risks.
  • Current legislation is often reactionary; proactive regulations are essential.
  • Regulations must strictly limit marketing and sales to minors and reduce overall product accessibility.