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Effect of electroacupuncture on diabetic neurogenic bladder: A randomized controlled trial protocol
Xuke Han1,2, Yang Gao1,2, Shengju Wang1,2
1Hospital of Chengdu University of Traditional Chinese Medicine.
Medicine
|April 26, 2020
Summary
Electroacupuncture (EA) combined with western medicine may improve diabetic neurogenic bladder (DNB) symptoms. This randomized controlled trial investigates the efficacy of EA plus basic western medicine for DNB management.
Area of Science:
- Neurology
- Urology
- Integrative Medicine
Background:
- Diabetic neurogenic bladder (DNB) is a common complication of diabetes mellitus, causing significant lower urinary tract issues.
- Acupuncture, particularly electroacupuncture (EA), shows promise in managing bladder dysfunction like urinary retention and incontinence.
- The optimal therapeutic strategy for DNB, especially combining EA with conventional treatments, requires further investigation.
Purpose of the Study:
- To evaluate the efficacy of electroacupuncture (EA) combined with basic western medicine for treating diabetic neurogenic bladder (DNB).
- To compare the therapeutic effects of EA alone, basic western medicine alone, and the combination of both in DNB patients.
- To analyze the additive or synergistic effects of combining EA with western medicine in DNB management.
Main Methods:
- A sham-controlled, patient-blinded, randomized controlled trial involving 150 eligible patients.
- Patients were divided into three groups: basic western medicine (BWC), EA with BWC, and sham EA with BWC.
- Interventions included 12 weeks of EA (twice weekly) or sham EA, alongside Alpha-lipoic acid (ALA) and methylcobalamin (MC) for BWC. Primary outcome assessed via 72-hour bladder diary; secondary outcomes include AUA-SI, PVR, and urodynamic tests.
Main Results:
- This section is to be filled after the study is completed and data is analyzed.
- The study is designed to provide data on the effectiveness of different treatment combinations.
- Results will indicate whether EA offers additional benefits when combined with standard western medicine for DNB.
Conclusions:
- This randomized controlled trial protocol outlines a clinical approach for managing DNB using acupuncture.
- The study will yield crucial information regarding the effectiveness of acupuncture, western medicine (ALA + MC), and their combination for DNB.
- Findings will elucidate the potential additive or synergistic therapeutic effects of integrating EA into DNB treatment regimens.
