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Practical recommendations for the management of diabetes in patients with COVID-19

Stefan R Bornstein1, Francesco Rubino2, Kamlesh Khunti3

  • 1Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany; Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital Carl Gustav Carus, Dresden, Germany; Department of Diabetes, School of Life Course Science and Medicine, King's College London, London, UK; Department of Endocrinology and Diabetology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.

The Lancet. Diabetes & Endocrinology
|April 27, 2020
PubMed

Insights

Diabetes significantly increases the risk of severe illness from coronavirus infections like COVID-19. This guidance offers practical management strategies for diabetes patients during the pandemic.

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Public Health

Background:

  • Diabetes is a critical comorbidity associated with severe outcomes in human pathogenic coronavirus infections, including SARS-CoV-2.
  • Individuals with diabetes face a higher risk of severe complications such as Adult Respiratory Distress Syndrome and multi-organ failure.
  • During the COVID-19 pandemic, 20-50% of patients globally had diabetes, highlighting a significant overlap.

Purpose of the Study:

  • To provide expert guidance and practical recommendations for managing diabetes during the COVID-19 pandemic.
  • To explore potential mechanistic links between novel coronavirus infection and diabetes.
  • To address the specific needs of diverse patient groups within the context of the pandemic.

Main Methods:

  • Convened an international panel of diabetes and endocrinology experts.
  • Synthesized current knowledge on coronavirus-diabetes interactions.
  • Developed evidence-based management strategies and recommendations.

Main Results:

  • Identified key mechanistic links between coronavirus infection and diabetes pathophysiology.
  • Formulated practical recommendations for diabetes management during the pandemic.
  • Highlighted differential management needs for various patient subgroups.

Conclusions:

  • Effective management of diabetes is crucial for mitigating severe outcomes in coronavirus infections.
  • Expert consensus provides essential guidance for healthcare providers.
  • Understanding patient-specific needs is vital for optimal pandemic response in diabetic populations.

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