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Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide

Christoph Steeneck1, Christian Gege1, Olaf Kinzel1

  • 1Phenex Pharmaceuticals AG, Waldhofer Str 104, 69123 Heidelberg, Germany.

Bioorganic & Medicinal Chemistry Letters
|April 27, 2020
PubMed

Keywords:
Autoimmune diseasesBioisostereNuclear receptorOxadiazoleRORcRORγt

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