Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

'Programmed' left ventricular angiography: a new method for assessing left ventricular compliance.

M Di Donato1, G A Barletta, F Fantini

  • 1Cattedra di Malattie dell'Apparato Cardiovascolare, Università di Firenze, Italia.

Cardiology
|January 1, 1988
PubMed
Summary

A new method uses a postextrasystolic beat during angiography to assess left ventricular chamber compliance. This technique reveals significant differences in diastolic function in patients with coronary artery disease and systolic dysfunction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patterns of Mental Health Service Use in Australian Workers with Low Back Pain: A Retrospective Cohort Study.

Journal of occupational rehabilitation·2024
Same author

The Prevalence of Mental Health Service Use in Australian Workers with Accepted Workers' Compensation Claims for Low Back Pain: A Retrospective Cohort Study.

Journal of occupational rehabilitation·2023
Same author

SARS-CoV-2 in the sweat of COVID-19-positive patients: a possible route of transmission?

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Relapse of chilblain-like lesions during the second wave of coronavirus disease 19.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Response to 'No evidence of SARS-CoV-2 infection by polymerase chain reaction or serology in children with pseudo-chilblain'.

The British journal of dermatology·2020
Same author

Acral cutaneous lesions in the time of COVID-19.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020

Area of Science:

  • Cardiology
  • Physiology

Background:

  • Left ventricular chamber compliance is a crucial parameter for assessing diastolic function.
  • Evaluating compliance traditionally involves complex measurements.
  • A simpler, effective method is needed for clinical application.

Purpose of the Study:

  • To introduce and validate a novel method for assessing left ventricular chamber compliance.
  • To evaluate the clinical utility of this method in patients with coronary artery disease.

Main Methods:

  • A programmed postextrasystolic beat was induced during left ventricular angiography using a temporary pacing catheter.
  • Measurements of end-diastolic pressure and end-diastolic volume index were obtained in basal and postextrasystolic beats.
  • The modulus of chamber stiffness, left ventricular chamber compliance (dV/dP), and specific compliance (dV/VdP) were calculated.

Related Experiment Videos

Main Results:

  • The study included 32 patients with coronary artery disease and 5 normal subjects.
  • Diastolic indices differed significantly between patient subgroups with varying disease severity and systolic dysfunction.
  • Patients with more severe coronary artery disease and systolic dysfunction exhibited higher chamber stiffness and lower compliance.

Conclusions:

  • The novel postextrasystolic beat method effectively evaluates left ventricular chamber compliance.
  • This method identifies impaired diastolic function in patients with coronary artery disease and systolic dysfunction.
  • The assessed indices correlate with left ventricular filling, offering clinical relevance.