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Updated: Dec 23, 2025

Bioprinting of Hydrogel Tumor Slices as a 3D Model for Mantle Cell Lymphoma
Published on: September 12, 2025
An update on options of therapy for aggressive mantle cell lymphoma
Jia Ruan1, Samuel Yamshon1, Koen van Besien1
1Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA.
Abstract:
With the emerging application of novel targeted agents in the induction, maintenance and salvage strategies, management of aggressive mantle cell lymphoma is being transformed from high-intensity chemo-immunotherapy applicable to only selected patients, to more personalized treatment incorporating novel agents that are effective and accessible for the majority of the patients. This review summarizes risk-stratified management paradigm for aggressive mantle cell lymphoma, providing context for clinical applications of novel agents and cellular therapy including stem cell transplant and CAR-T.
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