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CD123 as a Therapeutic Target Against Malignant Stem Cells

Mayumi Sugita1, Monica L Guzman2

  • 1Division of Hematology and Medical Oncology, Weill Cornell Medical College, 1300 York Avenue, C-660B, New York, NY 10065, USA.

Hematology/Oncology Clinics of North America
|April 28, 2020
PubMed
Summary

Leukemic stem cells (LSCs) in acute myeloid leukemia share markers with normal hematopoietic stem cells (HSCs) but have unique features. CD123 is a promising target for eliminating LSCs.

Keywords:
Acute myeloid leukemia (AML)BPDCNCD123Leukemic stem cell (LSC)Targeted therapy

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