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Trends in cervical cancer incidence in sub-Saharan Africa
Elima Jedy-Agba1, Walburga Yvonne Joko2, Biying Liu3
1International Research Center of Excellence, Institute of Human Virology, Abuja, Nigeria. elima.jedyagba@gmail.com.
Background:
Cervical cancer is the second most common cancer and the leading cause of cancer death in women in sub-Saharan Africa (SSA).
Methods:
Trends in the incidence of cervical cancer are examined for a period of 10-25 years in 10 population-based cancer registries across eight SSA countries (Gambia, Kenya, Malawi, Mauritius, Seychelles, South Africa, Uganda and Zimbabwe). A total of 21,990 cases of cervical cancer were included in the analyses.
Results:
Incidence rates had increased in all registries for some or all of the periods studied, except for Mauritius with a constant annual 2.5% decline. Eastern Cape and Blantyre (Malawi) registries showed significant increases over time, with the most rapid being in Blantyre (7.9% annually). In Kampala (Uganda), a significant increase was noted (2.2%) until 2006, followed by a non-significant decline. In Eldoret, a decrease (1998-2002) was followed by a significant increase (9.5%) from 2002 to 2016.
Conclusion:
Overall, cervical cancer incidence has been increasing in SSA. The current high-level advocacy to reduce the burden of cervical cancer in SSA needs to be translated into support for prevention (vaccination against human papillomavirus and population-wide screening), with careful monitoring of results through population-based registries.
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