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Updated: Dec 23, 2025

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Determination of Iodine Content in Dairy Products by Inductively Coupled Plasma Mass Spectrometry
Kathryn A Vance1, Amir Makhmudov1, Gulchekhra Shakirova1
1Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Inorganic and Radiation Analytical Toxicology Branch 4770 Buford Hwy NE, MS F-18, Atlanta, GA 30341, USA.
Abstract:
A probing study to establish a reliable and robust method for determining the iodine concentration using the ELAN® DRC™ II ICP-MS was performed in combination with a sample digestion and filtration step. Dairy products from locally available sources were evaluated to help determine the possibility and need for further evaluations in relation to the U.S. population's iodine intake. Prior to analysis, the samples were aliquoted and digested for 3 hours at 90±3 °C. Dilution and filtration were performed, following the digestion. The sample extract was analyzed, and the results were confirmed with NIST SRM 1549a Whole Milk Powder. Further experimentation will need to be performed to optimize the method for projected sample concentration and throughput.
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