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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
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Autoimmune Hepatitis Associated With Turmeric Consumption.

Brian S Lee1, Taruna Bhatia2, Charles T Chaya2

  • 1Department of Internal Medicine, University of California, Riverside School of Medicine, Riverside, CA.

ACG Case Reports Journal
|April 28, 2020
PubMed
Summary
This summary is machine-generated.

Turmeric, often seen as safe, can cause liver injury in some individuals. Discontinuing turmeric supplements helped one patient

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Area of Science:

  • Integrative Medicine
  • Hepatology
  • Clinical Toxicology

Background:

  • Turmeric is a widely used herbal supplement with perceived safety and liver-protective benefits.
  • Recent case reports suggest a potential link between turmeric consumption and drug-induced liver injury.
  • Distinguishing turmeric-induced liver injury from other liver conditions like autoimmune hepatitis is crucial.

Observation:

  • A 55-year-old woman presented with symptoms initially diagnosed as acute autoimmune hepatitis.
  • She had a history of chronic turmeric consumption.
  • The patient declined conventional steroid treatment.

Findings:

  • Discontinuation of turmeric supplementation was recommended.
  • Within one month, the patient's liver function tests normalized.
  • This suggests a causal link between turmeric intake and liver injury in this case.

Implications:

  • Highlights the potential for adverse effects from herbal supplements, including turmeric.
  • Underscores the importance of a thorough patient history, including supplement use, in diagnosing liver conditions.
  • Suggests clinicians should consider herbal supplement-induced liver injury in differential diagnoses.