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Updated: Dec 23, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic Enterocolitis: Gastric Outlet Obstruction
Shana Kothari1, Imad Elkhatib2
1Department of Internal Medicine, University of Illinois at Chicago, Advocate Christ Medical Center, Oak Lawn, IL.
Abstract:
Eosinophilic enterocolitis is a rare condition representing the least frequent manifestation of eosinophilic gastrointestinal disorders. We report a 49-year-old man who presented with abdominal pain, diarrhea, and intractable vomiting for 2 weeks. Abdominal computed tomography demonstrated gastric wall thickening with mural wall thickening of the small intestine and colon. Endoscopy revealed gastric outlet obstruction because of luminal stenosis from duodenal edema. Peripheral eosinophilia, endoscopic mucosal biopsies, and exclusion of differential diagnoses confirmed eosinophilic enterocolitis. The patient was successfully treated with a 4-week prednisone taper.
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