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Ocular nonsteroidal inflammatory drugs: where do we stand today?
S A Kandarakis1, P Petrou1, E Papakonstantinou1
1Department of Ophthalmology, National and Kapodistrian University of Athens, 1st University Eye Clinic, G. Gennimatas General Hospital, Athens, Greece.
Cutaneous and Ocular Toxicology
|April 28, 2020
Summary
Nonsteroidal anti-inflammatory drugs (NSAIDs) are vital in ophthalmology for treating various conditions and post-operative care. This review details their actions, uses, and side effects in eye diseases.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) have expanded therapeutic applications in ophthalmology.
- Despite a controversial history, NSAIDs are effective anti-inflammatory agents for diverse ocular diseases.
Purpose of the Study:
- To systematically review ocular NSAIDs available.
- To detail their mechanisms of action, indications, and potential side effects in ophthalmology.
Main Methods:
- Systematic review of ocular NSAIDs.
- Analysis of mechanisms, indications, and adverse events.
Main Results:
- NSAIDs are integral to surgical protocols for common ophthalmic operations like cataract surgery.
- They are widely used for conjunctivitis, retinal and choroidal diseases, and other inflammatory conditions.
- Despite potential adverse events, their therapeutic importance in ophthalmology remains significant.
Conclusions:
- Ocular NSAIDs offer significant therapeutic benefits in ophthalmology.
- Understanding their varied actions and side effects is crucial for optimal patient management.
- This review provides a comprehensive overview of available ocular NSAIDs.
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