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Decision-making in major depressive disorder: Subjective complaint, objective performance, and discrepancy between
Carolina Baeza-Velasco1, Sébastien Guillaume2, Emilie Olié2
1Département d'Urgence & Post Urgence Psychiatrique, Neuropsychiatrie: recherche épidémiologique et clinique, INSERM, Université Montpellier, CHU Montpellier, Montpellier, France; University of Paris, LPPS, Institut de Psychologie, 71 Avenue Édouard Vaillant, Boulogne-Billancourt F-92100, France.
Journal of Affective Disorders
|April 28, 2020
Summary
Objective and subjective decision-making impairment in major depressive disorder (MDD) are not associated. Both objective decision-making impairment and subjective decision-making impairment assessments are crucial for understanding cognitive function in MDD patients.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Major Depressive Disorder (MDD) is associated with cognitive deficits.
- Research comparing objective and subjective cognitive assessments in MDD is limited, particularly concerning decision-making.
- Decision-making impairment is a significant aspect of cognitive dysfunction in MDD.
Purpose of the Study:
- To investigate objective decision-making impairment (O-DMI) and subjective decision-making impairment (S-DMI) in individuals with MDD.
- To examine the association between O-DMI and S-DMI in this population.
- To identify factors associated with decision-making impairment status and discrepancies.
Main Methods:
- A cross-sectional study involving 109 participants diagnosed with MDD.
- Objective decision-making was assessed using the Iowa Gambling Task (identifying O-DMI).
- Subjective decision-making impairment was measured using item 9 of the Beck Depression Inventory (S-DMI), alongside data on psychiatric history, medication adherence, trauma, pain, and life experiences.
Main Results:
- 46% of participants exhibited O-DMI, and 65.1% reported S-DMI.
- No significant association was found between O-DMI and S-DMI.
- Negative life events predicted O-DMI, while depression severity and medication adherence predicted S-DMI. These factors also influenced the discrepancy between objective and subjective measures.
Conclusions:
- Confirms a lack of association between objective and subjective measures of decision-making in MDD.
- Highlights the importance of utilizing both objective and subjective assessments for a comprehensive understanding of cognitive functioning in MDD.
- Suggests tailored interventions may be needed based on individual cognitive profiles.
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