Related Experiment Videos
Nickel allergy: tolerance to metallic surface-plated samples in nickel-sensitive humans and guinea pigs
C Cavelier1, J Foussereau, P Gille
1Institut National de Recherche et de Sécurité, Vandoeuvre, France.
Contact Dermatitis
|November 1, 1988
Abstract:
The purpose of this work is to evaluate in nickel-sensitive patients and guinea pigs the tolerance to nickel samples, surface-plated with one or several metals of varying structures and thicknesses. All the metal samples elicited allergic reactions in the guinea pig. In humans, absolute tolerance was not observed for any sample. In humans, the interposing of a layer of bright copper between nickel and surface chrome greatly increased the tolerance.