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Published on: March 22, 2012
Aspergillus endophthalmitis: Potential role for vitreous galactomannan testing?
Damien Dupont1, Julien Saison2, Patrick Miailhes2
1Hospices Civils de Lyon, Institut de Parasitologie et Mycologie Médicale, Hôpital de la Croix-Rousse, Lyon, France, Université Claude Bernard Lyon I, Lyon, France; Université Claude Bernard Lyon 1, Integrative Physiology of the Brain Arousal Systems, Centre de Recherche en Neurosciences de Lyon, INSERM U1028-CNRS UMR5292, Lyon, France.
Diagnosing invasive fungal eye infections like ocular aspergillosis is difficult. This case suggests Aspergillus antigen testing in vitreous humor may aid diagnosis when standard methods fail.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Transplant Surgery
Background:
- Invasive aspergillosis can affect the eyes, but ocular involvement is infrequently documented.
- Diagnosing fungal endophthalmitis presents significant biological challenges.
- Heart transplant recipients are immunocompromised, increasing susceptibility to opportunistic infections.

