Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

326
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
326
Feedback control systems01:26

Feedback control systems

628
Feedback control systems are categorized in various ways based on their design, analysis, and signal types.
Linear feedback systems are theoretical models that simplify analysis and design. These systems operate under the principle that their output is directly proportional to their input within certain ranges. For instance, an amplifier in a control system behaves linearly as long as the input signal remains within a specific range. However, most physical systems exhibit inherent nonlinearity...
628
Two-Compartment Open Model: Overview01:05

Two-Compartment Open Model: Overview

455
Multicompartmental models are crucial tools in pharmacokinetics, providing a framework to understand how drugs move within the body. The two-compartment model is a crucial subtype, segmenting the body into central and peripheral compartments. The central compartment represents areas with high blood flow, such as plasma and highly perfused organs like the kidneys and liver, while the peripheral compartment signifies tissues with lower blood flow, like adipose tissue and muscle tissue.
The...
455
Control Systems01:10

Control Systems

1.7K
Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...
1.7K
Multiple Pipe Systems01:21

Multiple Pipe Systems

1.1K
Multipipe systems consist of complex configurations of interconnected pipes designed to transport fluids efficiently across intricate networks. They are essential in engineering applications requiring precise control over flow distribution, pressure, and head loss. They are categorized into series, parallel, loop, and network configurations, each distinguished by unique flow characteristics and applications.
Series Configuration
In a series configuration, fluid flows sequentially from one pipe...
1.1K
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

195
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
195

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acceptance of COVID-19 vaccination at different hypothetical efficacy and safety levels in ten countries in Asia, Africa, and South America.

Narra J·2024
Same author

Vaccine hesitancy among communities in ten countries in Asia, Africa, and South America during the COVID-19 pandemic.

Pathogens and global health·2021
Same author

Impact of COVID-19 on cancer care in India: a cohort study.

The Lancet. Oncology·2021
Same author

Response to 'Duplex systems: Top down or bottom-up approach?

Journal of pediatric urology·2021
Same author

Hypoxic changes to the urothelium as a bystander of end-stage bladder disease.

Journal of pediatric urology·2019
Same author

Clinical utility of <sup>188</sup>Rhenium-hydroxyethylidene-1,1-diphosphonate as a bone pain palliative in multiple malignancies.

World journal of nuclear medicine·2018
Same journal

Letter to the Editor re: "ChatGPT-4o's performance on pediatric vesicoureteral reflux".

Journal of pediatric urology·2026
Same journal

Letter to the Editor re: "Comparative analysis of three chatbot responses on pediatric primary nocturnal enuresis".

Journal of pediatric urology·2026
Same journal

Bypassing the emergency department for testicular torsion.

Journal of pediatric urology·2026
Same journal

Sociodemographic and clinical characteristics associated with nocturnal enuresis among children in a tertiary care center in Cairo, Egypt: A cross-sectional study.

Journal of pediatric urology·2026
Same journal

Neurocorrelates of nocturnal enuresis in pre-adolescent children.

Journal of pediatric urology·2026
Same journal

Response to Letter to the Editor re: "Comparative analysis of three chatbot responses on pediatric primary nocturnal enuresis".

Journal of pediatric urology·2026
See all related articles

Related Experiment Video

Updated: Dec 23, 2025

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
09:49

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Published on: April 16, 2014

26.7K

Duplex systems: Top-down or bottom-up approach?

D J B Keene1, R Subramaniam2

  • 1Department of Paediatric Urology, Royal Manchester Children's Hospital, Oxford Road, Manchester, M13 9WL, UK.

Journal of Pediatric Urology
|April 29, 2020
PubMed
Summary
This summary is machine-generated.

Bladder reconstructive surgery (BRS) is more effective than heminephroureterectomy (HN) for managing symptomatic duplex kidney disease, reducing the need for subsequent operations. This approach is particularly beneficial for patients with reflux or ureterocele.

Keywords:
DuplexHeminephrectomyMureteric reimplantationRefluxUreterocele

More Related Videos

Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

20.3K
Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
09:54

Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence

Published on: March 8, 2020

5.6K

Related Experiment Videos

Last Updated: Dec 23, 2025

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
09:49

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Published on: April 16, 2014

26.7K
Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

20.3K
Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
09:54

Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence

Published on: March 8, 2020

5.6K

Area of Science:

  • Urology
  • Pediatric Surgery
  • Nephrology

Background:

  • Duplex kidney systems present complex surgical challenges including reflux, ureterocele, obstruction, and ectopic ureteric insertion.
  • Current decision-making algorithms for surgical approach lack consensus, necessitating comparative outcome studies.

Purpose of the Study:

  • To compare the likelihood of requiring further surgery after an upper urinary tract approach (heminephroureterectomy) versus a lower urinary tract approach (bladder reconstructive surgery) for duplex systems.

Main Methods:

  • A prospective database of 79 patients undergoing surgery for duplex systems between 2003-2015 was analyzed.
  • Patients were divided into two groups: Group 1 (initial heminephroureterectomy) and Group 2 (initial bladder reconstructive surgery).
  • Outcomes, including the need for subsequent procedures (EI, BRS, ECR, HN), were recorded and statistically analyzed using Fisher's exact test.

Main Results:

  • Further surgery was required in 21% of patients in Group 1 (HN) versus 5% in Group 2 (BRS), a statistically significant difference (p=0.048).
  • Patients with both reflux and ureterocele had a higher chance of requiring further surgery after HN compared to BRS (p=0.01).
  • No patients experienced urinary retention or required catheterization post-surgery.

Conclusions:

  • Bladder reconstructive surgery (BRS) significantly reduces the need for re-operation compared to heminephroureterectomy (HN) in symptomatic duplex kidney patients.
  • BRS is a preferred approach for managing duplex systems complicated by dilating vesicoureteric reflux or ureterocele.
  • The study highlights the effectiveness of a lower urinary tract approach in minimizing subsequent surgical interventions.