Performance of the Patient-Reported Outcome Measurement Information System in Patients With Patellofemoral...

Area of Science:

• Orthopedics and Sports Medicine
• Rehabilitation and Physical Therapy
• Health Outcomes Research

Background:

• The Patient-Reported Outcome Measurement Information System (PROMIS) was developed to enhance patient-reported outcome measures (PROMs) using computer adaptive testing (CAT).
• The PROMIS physical function-CAT (PF-CAT) has not been previously evaluated in patients diagnosed with patellofemoral instability (PFI).

Purpose of the Study:

• To assess the construct validity of the PROMIS PF-CAT in patients with PFI by comparing it with established PROMs.
• To test the hypothesis that PF-CAT would correlate strongly with physical function PROMs and moderately with other health domain PROMs.

Main Methods:

• A cohort study design was employed, enrolling patients undergoing operative intervention for PFI (Level of evidence, 2).
• Preoperative PROMs administered included PROMIS PF-CAT, SF-36, KOOS, EQ-5D, and AKPS.
• Correlation coefficients and floor/ceiling effects were analyzed; statistical significance was set at P < .05.

Main Results:

• Ninety-one patients (63.7% female, mean age 20.1 years) completed the study; PF-CAT required the fewest questions (mean 4.3).
• PF-CAT demonstrated strong correlations with SF-36 PF subscale (r=0.78), AKPS (r=0.68), and KOOS ADL (r=0.68).
• Moderate correlations were observed with other KOOS subscales, and no floor or ceiling effects were found for PF-CAT.

Conclusions:

• The PROMIS PF-CAT exhibits strong construct validity in patients with PFI, correlating well with physical function measures and moderately with other health domains.
• The PF-CAT offers a low respondent burden and lacks floor or ceiling effects, making it a potentially beneficial tool.
• PROMIS PF-CAT is a viable alternative to existing PROMs for the preoperative assessment of physical function in patients with PFI.