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Related Experiment Video

Updated: Dec 23, 2025

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models

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Published on: October 27, 2023

Vital Pulp Therapy an Insight Over the Available Literature and Future Expectations.

Samer Nagui Hanna¹, Ruth Perez Alfayate², James Prichard¹

¹Department of Endodontic, College of Medicine and Dental School, UK.

European Endodontic Journal

|April 29, 2020

Summary

Vital pulp therapy (VPT) preserves compromised pulp tissue, offering advantages over root canal treatment. Newer biological scaffolds show promise for dentin regeneration and improved tooth strength.

Keywords:

Biomaterials based scaffolds direct pulp capping indirect pulp capping tricalcium silicate materials vital pulp therapy

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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

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Published on: January 12, 2017

Area of Science:

Dentistry
Biomaterials Science

Background:

Vital pulp therapy (VPT) aims to preserve compromised dental pulp, avoiding conventional root canal treatment.
VPT offers benefits like maintaining masticatory function and sensory feedback, crucial for early caries detection.

Purpose of the Study:

To review current materials used for vital pulp therapy (direct pulp capping).
To aid clinicians in evidence-based material selection for optimal patient outcomes.
To explore future material developments in pulp capping.

Main Methods:

Extensive literature search for recent data on direct pulp capping materials.
Analysis of synthetic, biological scaffolds, and composite materials.
Evaluation of emerging materials for dentin regeneration.

Main Results:

A variety of materials are available for pulp capping, ranging from synthetic to biological options.
Newly developed biological scaffolds demonstrate potential for dentin regeneration.
These scaffolds may strengthen tooth structure and mitigate risks associated with current materials.

Conclusions:

Clinicians need a comprehensive understanding of available VPT materials for informed decision-making.
Biological scaffolds represent a promising advancement in vital pulp therapy.
Future research should focus on harnessing regenerative potential for enhanced tooth preservation.