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Changes in sulfhydryl compounds in plasma, liver and brain after acute and chronic acetaldehyde administration in
R Farbiszewski1, M Chwiećko, A Hołownia
1Department of Inorganic and Analytical Chemistry, Medical Academy, Białystok, Poland.
Drug and Alcohol Dependence
|October 1, 1988
Abstract:
The content of sulfhydryl compounds in proteins and non-proteins of plasma, liver and brain after acute and chronic administration of acetaldehyde (ACH) was investigated in rats. After ACH 1.5% w/v ingestion for 1 and 4 weeks (0.3 ml/kg) daily, proteins and non-proteins in plasma and liver were decreased significantly. After acute ACH administration SH-groups in brain proteins were not significantly decreased, but in the brain non-proteins these groups were increased significantly.