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Updated: Dec 23, 2025

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Published on: October 3, 2018
The Multifunctional Dioxygenases of Gibberellin Synthesis
Theo Lange1, Maria João Pimenta Lange1
1Institut für Pflanzenbiologie, Technische Universität Braunschweig, Mendelssohnstr. 4, D-38106 Braunschweig, Germany.
Abstract:
Gibberellin (GA) hormones regulate the development of plants and their responses to environmental signals. The final part of GA biosynthesis is catalyzed by multifunctional 2-oxoglutarate-dependent dioxygenases, which are encoded by multigene families. According to their enzymatic properties and physiological functions, GA-oxidases are classified as anabolic or catabolic enzymes. Together they allow complex regulation of the GA biosynthetic pathway, which adapts the specific hormonal needs of a plant during development and interaction with its environment. In this review, we combine recent advances in enzymatic characterization of the multifunctional GA-oxidases, in particular, from cucumber and Arabidopsis that have been most comprehensively investigated.
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