Novel reconstruction algorithm of magnetoacoustic tomography based on ring transducer array for acoustic speed...

Magnetoacoustic tomography with magnetic induction (MAT-MI) is a technique that utilizes the acoustic signals induced by magnetic stimulation to reconstruct the electrical impedance distribution in biological tissues. Most algorithms ignored the fact that acoustic properties in human tissues are heterogeneous, which lead to distortion and blurring of small reconstructed objects. In this study, a novel algorithm is proposed for exact reconstruction of the sound source distribution in acoustic heterogeneous tissues.

Based on the ring transducer array, we develop an algorithm which combines algebraic reconstruction technique (ART) and time reversal method. Different to existing reconstruction methods, the ultrasonic transmission tomography (UTT) and the MAT-MI can be completed in same system, which decreases the system complexity. The sound velocity distribution is reconstructed with the ART so that the propagation time of the magnetoacoustic signals in the heterogeneous tissue is corrected. And then, the sound source image is reconstructed based on the time reversal method from new sound pressure data. Both numerical simulations and phantom experiments are established to validate the proposed method.

Compared with the results without consideration of the variation on acoustic speed, sound sources reconstructed by our method are more consistent with the model in terms of size and shape.

The novel algorithm can be used to reconstruct the high-accuracy image of MAT-MI sound source in the sound velocity inhomogeneous media. In addition, this method is applicable to scenarios that the prior knowledge of the imaging targets is unknown. The signal acquisition time of MAT-MI in acoustically heterogeneity media is greatly reduced due to the introduction of ring transducer array into the imaging system. Therefore, our method will promote the application of MAT-MI in noninvasive early diagnosis of tumor for preclinical study.