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Electrical conductance measurement of HgII-mediated DNA duplex in buffered aqueous solution
Ryo Yamada1, Issei Nomura1, Yuki Yamaguchi1
1Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan.
Abstract:
Electrical properties of metal-mediated DNA duplexes (metallo-DNA) have been of particular interest because of their potential applications in DNA-based nanoelectronics. We prepared HgII-mediated DNA duplex with NH2 anchors and measured the electrical conductance of single-molecule metallo-DNA via scanning tunneling microscopy-based break junction method in the buffered solution. Three conductance values were observed that may correspond to different conformations of the metallo-DNA molecule bridged over metallic electrodes.

