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Updated: Dec 23, 2025

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Published on: March 14, 2025
[In vitro study of apical negative pressure irrigation on apical extrusion and E. faecalis elimination]
Jia-Ping Lu1, Zheng-Wei Huang, Wen-Hao Qian
1Department of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011.
Purpose:
To compare the efficiency of negative pressure irrigation and conventional syringe irrigation and evaluate the possibility as a new way of irrigation.
Methods:
In vitro silicone socket model was used to simulate the resistance of apical flow by apical surrounding tissues. The in vitro efficacy on apical extrusion and E.faecalis elimination between negative pressure irrigation and conventional syringe irrigation was compared. SPSS 17.0 software package was used for statistical analysis.
Results:
Negative pressure irrigation extruded less (P<0.05), and was more effective in E.faecalis elimination(P<0.05) than conventional syringe.
Conclusions:
Negative pressure irrigation is a promising irrigation technique during root canal therapy.

