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Probiotics with ameliorating effects on the severity of skin inflammation in psoriasis: Evidence from experimental

Hadi Atabati1, Seyed-Alireza Esmaeili2,3, Ehsan Saburi4,5

  • 1Department of Pharmacology and Physiology, Université de Montréal, Montreal, QC, Canada.

Journal of Cellular Physiology
|April 30, 2020
PubMed

Insights

Probiotics, beneficial gut bacteria, show promise in treating inflammatory skin conditions like psoriasis. By modulating the gut microbiome, they may help manage immune responses and improve skin health.

Area of Science:

  • Immunology
  • Microbiology
  • Dermatology

Background:

  • Probiotics are safe and beneficial as immunomodulatory medications.
  • Gastrointestinal bacteria critically influence inflammatory disorders beyond the gut.
  • Gut microbiome manipulation by probiotics shows potential for inflammatory skin diseases.

Purpose of the Study:

  • To review the impact of gastrointestinal microbiota on psoriasis pathogenesis.
  • To explore probiotic species used in psoriasis treatment through a literature survey.

Main Methods:

  • Literature survey and review of existing studies.

Main Results:

  • Psoriasis exhibits a distinct skin microbiome.
  • Probiotics modulate immune responses by altering the gut microbiome.
  • Probiotics demonstrate promising results in managing inflammatory skin conditions.

Conclusions:

  • The gut microbiome plays a significant role in psoriasis.
  • Specific probiotic species may be beneficial for psoriasis treatment.
  • Further research into probiotics for psoriasis is warranted.
Keywords:
Lactobacillusbifidobacteriacommensal microbiotaimmunomodulationpsoriasis

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