Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Novel Cloxyquin Analogs for K<sub>2P</sub>18.1 Channel Modulation.

Archiv der Pharmazie·2026
Same author

Light-responsive aggregation of vesicles using host-guest interaction of β-cyclodextrin and diazocine.

Chemical communications (Cambridge, England)·2026
Same author

Molecularly Engineered 2D Xene Heterostructures With Implanted Peroxidase-Like Activity for Mimicking Enzyme Functions.

Small methods·2026
Same author

Bio-modified hydrogels in electrolyte-gated organic field-effect transistors for sensing applications.

Nanoscale·2026
Same author

Chiral-Induced Spin-Polarized Molecular Switching in a Magneto-Controlled 2D System using Electrical Readouts.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Photoisomerization and Electrochemical Switching of Arylazopyrazoles in Self-Assembled Monolayers.

ACS applied materials & interfaces·2026

Related Experiment Video

Updated: Dec 23, 2025

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

18.6K

Cyclodextrin-based superparamagnetic host vesicles as ultrasensitive nanobiocarriers for electrosensing.

Jose Muñoz1, Núria Crivillers1, Bart Jan Ravoo2

  • 1Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), and CIBER-BBN, Campus de la UAB, 08193 Bellaterra (Cerdanyola del Vallès), Spain. mmas@icmab.es.

Nanoscale
|April 30, 2020
PubMed
Summary

Researchers developed novel magnetic cyclodextrin vesicles (mCDVs) for sensitive electrosensing. This magnetic nanohybrid probe enables highly sensitive picomolar determination of thyroxine (T4) using a nanocomposite carbon-paste electrode.

More Related Videos

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example
08:42

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

12.7K
Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.9K

Related Experiment Videos

Last Updated: Dec 23, 2025

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

18.6K
Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example
08:42

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

12.7K
Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.9K

Area of Science:

  • Nanotechnology
  • Electrochemistry
  • Biomedical Engineering

Background:

  • Superparamagnetic nanoparticles offer unique magnetic properties for sensing applications.
  • Amphiphilic β-cyclodextrins can form stable vesicles and exhibit host-guest chemistry.
  • Electrochemical sensing platforms require sensitive and specific biorecognition probes.

Purpose of the Study:

  • To engineer a novel carbohydrate-based nanohybrid probe for electrosensing.
  • To demonstrate the efficacy of magnetic cyclodextrin vesicles (mCDVs) for sensitive analyte detection.
  • To establish mCDVs as water-soluble magnetic nanobiocarriers for biosensing.

Main Methods:

  • Fabrication of a nanohybrid material combining superparamagnetic nanoparticles and amphiphilic β-cyclodextrins into vesicles (mCDVs).
  • Development of a magneto nanocomposite carbon-paste electrode (mNC-CPE) incorporating the mCDVs.
  • Electrochemical determination of thyroxine (T4) using the mCDVs/mNC-CPE system, leveraging host-guest interactions.

Main Results:

  • The engineered mCDVs exhibited synergistic properties when integrated onto the mNC-CPE.
  • Achieved highly sensitive picomolar determination of thyroxine (T4), surpassing existing electrochemical methods.
  • Demonstrated the potential of mCDVs as effective water-soluble magnetic nanobiocarriers.

Conclusions:

  • The developed mCDVs represent a novel and sensitive magnetic biorecognition probe for electrosensing.
  • This magnetic nanohybrid system offers a promising platform for electrochemical biosensing of various targets.
  • mCDVs are viable alternatives for supramolecular trace determination in complex matrices.