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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Large vessel occlusion is independently associated with atrial fibrillation detection

J Pagola1, J Juega1, J Francisco-Pascual2,3

  • 1Stroke Unit, Neurology Department and Medicine Department, Vall d'Hebrón Hospital and Autonomous University of Barcelona, Barcelona, Spain.

European Journal of Neurology
|April 30, 2020
PubMed

Insights

Early detection of paroxysmal atrial fibrillation (pAF) is crucial for preventing cardiac embolism. Large vessel occlusion in cryptogenic stroke is an independent marker for detecting pAF, aiding in timely intervention and stroke prevention.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Monitoring

Background:

  • Covert paroxysmal atrial fibrillation (pAF) is a primary cause of cardiac embolism.
  • Identifying early indicators of pAF is essential for stroke prevention.

Purpose of the Study:

  • To identify parameters associated with early detection of pAF in patients with cryptogenic stroke using intensive cardiac monitoring.
  • To evaluate the efficacy of continuous cardiac monitoring in identifying pAF in stroke patients.

Main Methods:

  • The Crypto-AF study involved continuous cardiac monitoring of non-lacunar cryptogenic stroke patients for 28 days.
  • Key parameters assessed included stroke severity, infarct patterns, large vessel occlusion (LVO), electrocardiography, Holter findings, left atrial volume index, and brain natriuretic peptide levels.

Main Results:

  • pAF was detected in 23.1% of patients.
  • Older age, hemorrhagic infarction, large vessel occlusion (LVO), larger left atrial volume index, and higher brain natriuretic peptide levels were associated with pAF detection.
  • LVO was independently associated with pAF detection and longer pAF episodes (>5 hours).

Conclusions:

  • Large vessel occlusion (LVO) in cryptogenic stroke is an independent predictor of paroxysmal atrial fibrillation (pAF).
  • Identifying LVO can aid in the early detection of pAF, facilitating timely treatment and reducing stroke recurrence.
Abstract

Keywords:
Holteratrial fibrillationcardiac embolismcerebrovascular diseases and cerebral circulation

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