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Updated: Dec 23, 2025

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Quadriceps Inhibition After Naturally Occurring Patellar Tendon Damage and Pain.

Steven M Davi1, Adam S Lepley2, Craig R Denegar1

  • 1Department of Kinesiology, University of Connecticut, Storrs.

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|April 30, 2020
PubMed
Summary

Knee injury and pain can lead to quadriceps weakness. Patellar tendinopathy (PT) with structural damage significantly impairs quadriceps neuromuscular function and strength compared to pain alone.

Keywords:
diagnostic imagingknee painmuscle inhibitiontendinopathy

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Area of Science:

  • Neuromuscular Function
  • Orthopedics
  • Sports Medicine

Background:

  • Knee joint injuries disrupt afferent signaling, leading to quadriceps inhibition and weakness.
  • The distinct roles of pain and structural damage in this inhibition are not fully understood.

Purpose of the Study:

  • To investigate how knee damage and pain influence quadriceps neuromuscular function in individuals with patellar tendinopathy (PT).

Main Methods:

  • A cross-sectional study involving 20 individuals with PT and 10 healthy controls.
  • Participants with PT were categorized into groups with (1) pain and structural tendon abnormality or (2) regional pain only.
  • Quadriceps inhibition and activation were assessed using the Hoffman reflex and central activation ratio.

Main Results:

  • Both PT groups showed reduced spinal-reflex excitability and quadriceps activation compared to controls.
  • Knee-extension strength was lower in the PT group versus controls.
  • Individuals with both pain and structural tendon abnormality (PT group) exhibited the most significant deficits, failing to meet clinical thresholds.

Conclusions:

  • Patellar tendinopathy, especially with structural damage, leads to significant deficits in quadriceps neuromuscular function and strength.
  • Pain alone has a less pronounced effect than combined pain and structural damage on quadriceps function.