Related Experiment Video
Updated: Dec 23, 2025

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
Published on: August 26, 2014
Addiction from the harmful dysfunction perspective: How there can be a mental disorder in a normal brain
1Silver School of Social Work, Department of Psychiatry, and Center for Bioethics, New York University, 1 Washington Square North, New York, NY 10025, United States.
Addiction is debated as a brain disease versus problematic choices. This analysis suggests addiction may be a motivational medical disorder, even without neurological dysfunction, impacting responsibility and control.
Area of Science:
- Medical Philosophy
- Neuroscience
- Addiction Studies
Background:
- Addiction is debated: is it a brain disease or a result of normal learning?
- The National Institute on Drug Abuse (NIDA) views addiction as a brain disease due to observed brain changes.
- Critics argue these changes stem from neuroplasticity, not disease, framing addiction as problematic choices.
Purpose of the Study:
- To evaluate addiction's status as a medical disorder using the harmful dysfunction analysis.
- To explore the evolutionary 'hijack' theory as an alternative explanation for addiction.
- To examine the implications of addiction as a motivational disorder for social responsibility and control.
Main Methods:
- Philosophical analysis of medical disorder criteria (harmful dysfunction analysis).
- Critique of the brain disease model of addiction.
- Evaluation of the evolutionary 'hijack' theory of addiction.
Main Results:
- Even if brain changes are due to neuroplasticity, addiction is not necessarily a matter of nondisordered choice.
- The evolutionary 'hijack' theory offers a framework for addiction as a motivational disorder.
- This perspective suggests addiction can be a disorder without underlying neurological dysfunction.
Conclusions:
- Addiction may be a distinct motivational medical disorder, independent of the brain disease model.
- The 'hijack' theory reframes addiction, impacting views on personal responsibility and societal interventions.
- Understanding addiction as a motivational disorder necessitates a re-evaluation of its causes and management.
Related Concept Videos
Drug Abuse and Addiction: Pharmacological Phenomena
Introduction to Psychological Disorders
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Obsessive-Compulsive Disorder

