Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rational design of Pickering emulsion-templated silica capsules loaded with ionic liquids: tailoring intrinsic textural properties <i>via</i> interfacial sol-gel kinetics.

Nanoscale·2026
Same author

Ligand-mediated formation of amphiphilic silver nanoclusters: synthesis, redox properties, and activity against clinically relevant bacteria.

Journal of materials chemistry. B·2026
Same author

DNA-hybridization on gold nanospheres: a dual-fluorescence investigation of surface loading and strand length effects.

Journal of biomedical optics·2026
Same author

Cryo-Correlative Light and X-ray Microscopies: Expanding the Intracellular Chemical Map.

ACS nano·2026
Same author

Tunable gelatin-coated biosynthesized gold nanotriangles: Thermoplasmonic performance and in vitro therapeutic potential via on-demand visible-NIR LED activation.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Recent Advances in Plasmon-Assisted Optical Sensing of Inflammatory Biomarkers.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology·2026

Related Experiment Video

Updated: Dec 23, 2025

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.7K

Microfluidic platform for integrated plasmonic detection in laminal flow.

Andreea Campu1,2, Frederic Lerouge3, Ana-Maria Craciun1

  • 1Nanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Treboniu Laurean No.42, Cluj-Napoca 400271, Romania.

Nanotechnology
|April 30, 2020
PubMed
Summary

We developed a portable microfluidic device with gold nanoparticles for sensitive, real-time analyte detection. This plasmonic-enhanced system offers high accuracy for various biosensing applications.

More Related Videos

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.3K

Related Experiment Videos

Last Updated: Dec 23, 2025

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.7K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.3K

Area of Science:

  • Nanotechnology
  • Plasmonics
  • Microfluidics

Background:

  • Microfluidic devices offer miniaturization and reduced analysis time.
  • Plasmonic transducers enhance sensitivity in biosensing applications.
  • Developing portable and robust sensing platforms is crucial for point-of-care diagnostics.

Purpose of the Study:

  • To design a novel, robust microfluidic device integrated with plasmonic transducers.
  • To achieve high sensitivity and portability for dynamic analyte measurements.
  • To enable real-time detection and identification of molecules in a microfluidic system.

Main Methods:

  • Controlled deposition of gold bipyramidal nanoparticles (AuBPs) on a glass substrate.
  • Integration of the plasmonic substrate into a polydimethylsiloxane (PDMS) microfluidic circuit.
  • Evaluation of localized surface plasmon resonance (LSPR) sensitivity and surface-enhanced Raman scattering (SERS) detection.

Main Results:

  • Achieved bulk sensitivity of 243 nm RIU-1 for isolated AuBPs and 150 nm RIU-1 for linked nanoparticles.
  • Demonstrated volumetric SERS detection of molecules in continuous flow using extrinsic 'hot-spots'.
  • Validated the system's capability for real-time analyte detection in laminar flow.

Conclusions:

  • The developed miniaturized, portable microfluidic system provides a robust platform for sensitive analyte detection.
  • The integrated plasmonic transducers enable high-accuracy, real-time measurements.
  • This work lays the foundation for advanced biosensing applications requiring portable and dynamic analysis.