Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

2.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.9K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.7K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

1.9K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.9K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

13.5K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.5K
Oral Hypoglycemic Agents: Biguanides and Glitazones01:26

Oral Hypoglycemic Agents: Biguanides and Glitazones

527
Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
527

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extremes on the benign-malignant tumour spectrum: Distinct transcriptomic landscapes between two common canine perianal neoplasms based on the hallmarks of cancer.

PloS one·2026
Same author

From Viscose to Lyocell-Type Fibers: Chemical Recycling of Viscose and Modal Fibers Using the Ioncell Process.

ChemSusChem·2026
Same author

68Ga-DOTA-exendin-4 PET/CT for Insulinoma Localization in Patients with Negative or Inconclusive Conventional Imaging.

The Journal of clinical endocrinology and metabolism·2026
Same author

Divergent myeloid and lymphoid immune landscapes in HPV/p16 positive and HPV/p16 negative oropharyngeal squamous cell carcinomas and their lymph node metastases.

Molecular medicine (Cambridge, Mass.)·2026
Same author

DNA methylation-based classification of hematolymphoid neoplasms.

Blood advances·2026
Same author

Therapy for Type 1 Diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2026

Related Experiment Video

Updated: Dec 23, 2025

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.2K

[Gestational diabetes - actual trends].

Michael Hummel, Helmut Kleinwechter, Katharina Laubner

    Deutsche Medizinische Wochenschrift (1946)
    |April 30, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Gestational diabetes (GDM) screening and treatment are vital for reducing maternal and child risks. Early detection and management, including lifestyle changes and insulin therapy, improve outcomes for both mother and baby.

    More Related Videos

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
    06:46

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

    Published on: July 5, 2022

    3.1K
    Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
    06:11

    Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

    Published on: May 17, 2024

    969

    Related Experiment Videos

    Last Updated: Dec 23, 2025

    Improving IV Insulin Administration in a Community Hospital
    12:08

    Improving IV Insulin Administration in a Community Hospital

    Published on: June 11, 2012

    19.2K
    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
    06:46

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

    Published on: July 5, 2022

    3.1K
    Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
    06:11

    Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

    Published on: May 17, 2024

    969

    Area of Science:

    • Obstetrics and Gynecology
    • Endocrinology
    • Public Health

    Background:

    • Gestational diabetes mellitus (GDM) is a condition affecting pregnant women, often asymptomatic.
    • Since 2012, GDM screening has been integrated into German maternity guidelines.
    • Early detection and management of GDM are crucial for mitigating risks to both mother and child.

    Purpose of the Study:

    • To outline the importance of GDM screening and treatment in Germany.
    • To describe the goals of GDM management, aiming for outcomes comparable to metabolically healthy pregnancies.
    • To detail therapeutic approaches and supportive measures for GDM.

    Main Methods:

    • Review of current GDM screening protocols within German maternity guidelines.
    • Description of therapeutic strategies including blood glucose monitoring, weight management, and fetal sonographic monitoring.
    • Discussion of pharmacotherapy options, with insulin as the gold standard.
    • Emphasis on integrated care models (maternity clinics with pediatric facilities) and breastfeeding promotion.

    Main Results:

    • Non-pharmacological therapy is effective in 70-90% of GDM cases.
    • Insulin remains the gold standard for pharmacotherapy when needed.
    • Specialized maternity clinics ensure optimal safety during birth.
    • Breastfeeding offers long-term health benefits for mother and child.

    Conclusions:

    • Comprehensive GDM management, encompassing screening, lifestyle interventions, and appropriate pharmacotherapy, is essential.
    • Integrated care and support for breastfeeding contribute significantly to positive maternal and child health outcomes.
    • Adherence to guidelines and specialized care improve the prognosis for pregnancies affected by GDM.