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Functional cognitive disorders: update on diagnostic status.
1Cognitive Function Clinic, Walton Centre for Neurology & Neurosurgery, Liverpool, UK.
Neurodegenerative Disease Management
|May 1, 2020
Summary
Functional cognitive disorders (FCD) affect patients without clear neurological causes. Diagnosis may rely on clinical profiles, with mood and sleep issues often co-occurring.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Science
Background:
- Many patients presenting with cognitive symptoms lack identifiable neurological explanations.
- A significant subset exhibits a discrepancy between subjective cognitive complaints and objective functional capacity.
- This diagnostic category is termed 'functional cognitive disorders' (FCD).
Purpose of the Study:
- To review the current understanding and evidence base for functional cognitive disorders (FCD).
- To explore diagnostic approaches and associated conditions within FCD.
Main Methods:
- Review of existing literature on functional cognitive disorders.
- Analysis of clinical profiles, including discourse and simple clinical signs.
- Examination of concurrent conditions such as mood and sleep disturbances.
Main Results:
- Research on FCD is nascent, with preliminary evidence supporting diagnosis through characteristic clinical presentations.
- Typical diagnostic indicators include specific patterns in language discourse and straightforward clinical observations.
- Functional cognitive disorders frequently co-occur with mood disorders, sleep disturbances, and other functional conditions.
Conclusions:
- Functional cognitive disorders represent a distinct diagnostic category requiring further investigation.
- Positive diagnosis of FCD appears feasible based on established clinical profiles.
- The underlying pathogenesis of FCD remains undetermined, with a potential role for metamemory dysfunction suggested.
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