Expandable Valves, Annuloplasty Rings, Shunts, and Bands for Growing Children

Eric N Feins1, Sitaram M Emani1

  • 1Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Insights

Pediatric heart surgery requires devices that accommodate growth. Current options necessitate reoperations, but new growth-accommodating technologies are emerging for better pediatric cardiac care.

Area of Science:

  • Pediatric Cardiac Surgery
  • Biomedical Engineering
  • Regenerative Medicine

Background:

  • Congenital heart surgery must account for pediatric somatic growth.
  • Existing pediatric valve repair lacks growth-accommodating prostheses, leading to reoperations.
  • Implant sizing for shunts, conduits, and pathways must consider current and future growth.

Purpose of the Study:

  • To define the clinical need for growth-accommodating devices in pediatric congenital heart surgery.
  • To review current and emerging technologies for growth accommodation in this field.

Main Methods:

  • Literature review of clinical needs and technological advancements.
  • Characterization of established and preclinical growth-accommodating technologies.

Main Results:

  • A significant unmet need exists for pediatric cardiac devices that accommodate somatic growth.
  • Several growth-accommodating technologies are in preclinical development, with some reaching the clinical arena.

Conclusions:

  • Developing growth-accommodating technologies is crucial to minimize reoperations in pediatric congenital heart surgery.
  • These innovations promise improved long-term outcomes for children requiring cardiac procedures.

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