Variation in small bowel transit time on capsule endoscopy
Related Experiment Video
Updated: Dec 22, 2025

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
Kentaro Tominaga1, Hiroki Sato1, Hiroshi Yokomichi2
1Division of Gastroenterology and Hepatology, Niigata University Medical and Dental Hospital, Niigata, Japan.
Background:
Small bowel motility remains inadequately understood because of the complex and various functions as well as its anatomical position. The aimed of the study was to investigate the small bowel transit time (SBTT) of capsule endoscopy (CE) and to analyze the clinical factors affecting SBTT.
Methods:
SBTT was analyzed in patients who underwent small bowel CE. Factors contributing to SBTT and CE retention were investigated.
Results:
Among 397 patients enrolled in this study, 336 (84.6%) completed CE. The mean SBTT (± standard deviation) was 282.1±132.2 min. According to the univariate and multivariate analyses, aging and small bowel stenosis extended SBTT. In 38 patients who underwent multiple CE studies, considerable variation in SBTT were observed [mean of standard deviations (SDs) =97.97 min, SD of the SDs =81.99 min]. CE retention was observed in 61 patients (13.3%), and it was statistically associated to small bowel lesion.
Conclusions:
Aging and small bowel stenosis were associated with longer SBTT. Furthermore, SBTT analyzed by CE should be interpreted carefully considering the intra-individual differences in SBTT.
Related Concept Videos
Endoscopic Procedures III: Video Capsule Endoscopy
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Noncompartmental Analysis: Mean Transit, Absorption and Dissolution Time
One of the key parameters is the mean transit time (MTT), which refers to the total duration required for drug molecules to transit through the body. MTT is determined by calculating the ratio of the area under the moment curve to the area...
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Factors Influencing Drug Absorption: Anatomical Parameters
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

