Tb-doped BSA-gold nanoclusters as a bimodal probe for the selective detection of TNT

Trinitrotoluene (TNT) is a widely used explosive belonging to the family of nitroaromatic compounds, and its misuse poses a significant threat to society. Herein, we propose a Tb-BSA-AuNC fluorescent and colorimetric sensing probe for the selective onsite detection of TNT in the aqueous phase. Tb-doped BSA-protected gold nanoclusters (Tb-BSA-AuNCs) were synthesized by a microwave-assisted method, and TNT detection was carried out utilizing the chemistry of Meisenheimer complex formation. Tb doping of gold nanoclusters was demonstrated to facilitate better electron shuttling effects and thereby improve the efficiency of complex formation between the TNT and gold nanoclusters. A paper strip assay was also developed for TNT detection with the designed probe. Limits of detection and quantification of 0.2136 mM and 0.7120 mM, respectively, were achieved. Graphical abstract.