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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

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The prevalence, diagnosis and surgical risk factors of spinal tuberculosis in children

Mao-Shui Wang1, Chao Han2, Jun-Li Wang3

  • 1Department of Lab Medicine, Shandong Provincial Chest Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Tropical Medicine & International Health : TM & IH
|May 3, 2020
PubMed

Insights

Childhood spinal tuberculosis (TB) in China is a significant public health issue. Early treatment initiation is crucial, as the condition requires more attention and research for effective management.

Area of Science:

  • Pediatric infectious diseases
  • Spinal tuberculosis epidemiology
  • Public health challenges in China

Background:

  • The burden of childhood spinal tuberculosis (TB) in China remains unquantified.
  • Current treatment strategies for pediatric spinal TB lack sufficient evidence.
  • This study addresses the need for data on childhood spinal TB in China.

Purpose of the Study:

  • To estimate the burden of childhood spinal TB in China.
  • To review clinical experiences with pediatric spinal TB.
  • To identify factors influencing treatment and outcomes.

Main Methods:

  • Retrospective analysis of medical records from 2006-2019.
  • Inclusion of pediatric patients (≤15 years) diagnosed with spinal TB.
  • Collection and analysis of demographic, clinical, laboratory, and radiological data.

Main Results:

  • Seventy-two cases of childhood spinal TB were identified, with a prevalence of 4.5% among childhood TB cases.
  • Diagnostic test positivity rates varied: T-SPOT.TB (29.6%), AFB smear (14.3%), mycobacterial culture (23.3%), TB RT-PCR (43.8%), and biopsies (88.5%).
  • The surgical rate was 40.3%, with pulmonary TB being a significant factor associated with the need for surgery (OR=4.000).

Conclusions:

  • Childhood spinal TB is a serious public health concern in China that requires increased attention.
  • Early diagnosis and timely treatment initiation are essential for managing pediatric spinal TB.
  • Further research is needed to develop evidence-based treatment guidelines.
Abstract

Keywords:
childhood spinal tuberculosisdiagnosisdiagnosticfacteur de risque chirurgicalprevalenceprévalencesurgical risk factortuberculose vertébrale infantile

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