Related Experiment Video

Updated: Dec 22, 2025

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

11.9K

[Lower-limb peripheral arterial disease]

C Le Hello1, L Fouillet2, C Boulon2

  • 1Département de Médecine Vasculaire et Thérapeutique, Centre Hospitalier Universitaire, Saint-Étienne, France; Campus Santé et Innovations, Université Jean Monnet, St-Priest-en-Jarez, France; INSERM, U1059 Sainbiose, Université de Lyon, Saint-Étienne, France.

La Revue De Medecine Interne
|May 4, 2020
PubMed

Insights

Peripheral arterial disease, often caused by atheroma, is underdiagnosed due to asymptomatic cases, particularly in women and diabetics. Early detection and adapted treatment, including risk factor modification and revascularization, are crucial for reducing mortality.

Area of Science:

  • Vascular Medicine
  • Cardiovascular Disease Epidemiology

Background:

  • Peripheral arterial disease (PAD) stems from atheroma and is prevalent in individuals with vascular risk factors and in low-income nations.
  • PAD is frequently underdiagnosed because patients are often asymptomatic, a presentation common in women and individuals with diabetes.
  • Atheroma in PAD commonly affects other arterial systems, notably the coronary arteries.

Purpose of the Study:

  • To highlight the significance of peripheral arterial disease (PAD) and its diagnostic methods.
  • To emphasize the importance of early detection and adapted treatment strategies for PAD.
  • To discuss the challenges in optimal patient management and achieving therapeutic targets in PAD.

Main Methods:

  • Diagnosis of PAD is primarily achieved through the calculation of the ankle-brachial index.
  • Treatment strategies involve correcting vascular risk factors such as tobacco cessation, implementing walking rehabilitation, and prescribing medications like antiplatelet agents, statins, and renin-angiotensin system blockers.
  • Revascularization is the primary treatment for critical or rest ischemia in PAD patients.

Main Results:

  • Peripheral arterial disease (PAD) is linked to atheroma and frequently occurs with vascular risk factors and in low-income countries.
  • The ankle-brachial index is the key diagnostic tool for PAD, which is often asymptomatic and thus underdiagnosed, especially in women and diabetics.
  • Effective treatment, including risk factor modification and revascularization when necessary, can significantly reduce the morbidity and mortality associated with PAD.

Conclusions:

  • Optimal management of peripheral arterial disease (PAD) is essential for reducing associated morbidity and mortality.
  • Addressing vascular risk factors, promoting lifestyle changes, and timely revascularization are key components of PAD treatment.
  • Despite established treatments, patient management in PAD often falls short of optimal, with therapeutic targets frequently unmet.

Keywords:
ArtériopathieDiagnosisDiagnosticEpidemiologyPeripheral arterial diseasePreventionPréventionTraitementTreatmentÉpidémiologie

More Related Videos

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

3.9K
Laser Doppler Perfusion Imaging in the Mouse Hindlimb14:45

Laser Doppler Perfusion Imaging in the Mouse Hindlimb

Published on: April 18, 2021

6.5K

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
253
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
222
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
239
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
176
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
254
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
3.9K