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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Disorders of the Female Reproductive System01:24

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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Infertility in Females01:28

Infertility in Females

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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Related Experiment Video

Updated: Dec 22, 2025

Isolation of Leukocytes from the Human Maternal-fetal Interface
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Isolation of Leukocytes from the Human Maternal-fetal Interface

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Maternal death due to COVID-19.

Sedigheh Hantoushzadeh1, Alireza A Shamshirsaz2, Ashraf Aleyasin3

  • 1Maternal Fetal Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.

American Journal of Obstetrics and Gynecology
|May 4, 2020
PubMed
Summary

Severe COVID-19 disease in pregnant women is unexpectedly fatal. This case series found that 7 out of 9 pregnant women with severe COVID-19 died, highlighting the critical risk to maternal health.

Keywords:
COVID-19SARS CoV-2 viruscoronavirus disease in pregnancylower respiratory infections in pregnancymaternal deathmaternal mortalitymaternal respiratory morbiditypregnancyrespiratory failure with COVID-19

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Area of Science:

  • Infectious Diseases
  • Obstetrics and Gynecology
  • Public Health

Background:

  • The global impact of COVID-19 (2.5 million infections, 169,000 deaths by April 2020) has shown few reported maternal deaths.
  • This is unexpected given higher risks observed in pregnant women during previous coronavirus (SARS-CoV, MERS-CoV) and influenza outbreaks.
  • The potential for severe outcomes in pregnant individuals with COVID-19 warrants further investigation.