Related Experiment Video
Updated: Dec 22, 2025
04:04
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
280
Mandibular Intraosseous Angiofibroma-A Rare Clinical Entity
Ami Amini-Salari1, Krzysztof Glomski2, David Ahn3
1Resident, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA.
Summary
A rare intraosseous mandibular angiofibroma, a benign vascular tumor, was diagnosed in a 23-year-old male. This case highlights an extremely uncommon presentation of angiofibroma in the jawbone.
Area of Science:
- Oncology
- Head and Neck Surgery
- Oral and Maxillofacial Pathology
Background:
- Angiofibromas are rare, benign, highly vascular tumors typically found in the nasopharynx.
- They predominantly affect adolescent males and are known for local invasiveness.
- Maxillofacial region angiofibromas are exceptionally uncommon.
Observation:
- A case report of an intraosseous mandibular angiofibroma in a 23-year-old male patient is presented.
- The tumor's location within the mandibular bone is a highly unusual characteristic.
- Histomorphologic and molecular analyses confirmed the diagnosis.
Findings:
- This represents one of the very few reported instances of angiofibroma occurring specifically within the mandible.
- The tumor exhibited typical benign angiofibroma characteristics but in an atypical intraosseous location.
- Confirmation involved detailed pathological examination.
Implications:
- This case expands the known anatomical distribution of angiofibromas.
- It underscores the importance of considering rare tumor presentations in the maxillofacial region.
- Further research may elucidate specific factors contributing to intraosseous angiofibroma development.
