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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

879
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
879

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Advanced-PRF: Clinical evaluation in impacted mandibular third molar sockets.

N Gupta1, S Agarwal2

  • 1Department of Oral and Maxillofacial Surgery, Identity ENT & Dental Centre, Dehradun (U.K) 248001, India.

Journal of Stomatology, Oral and Maxillofacial Surgery
|May 4, 2020
PubMed
Summary

Advanced PRF (A-PRF) significantly enhances healing of soft tissue and bone in mandibular third molar extraction sockets. This advanced platelet-rich fibrin formulation reduces postoperative pain, swelling, and trismus, improving patient comfort and surgical outcomes.

Keywords:
A-PRFImpacted mandibular third molar socket healingPainSwellingTrismus.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Regenerative Medicine
  • Biomaterials

Background:

  • Impacted mandibular third molar extractions are common surgical procedures.
  • Postoperative complications include pain, swelling, trismus, and delayed healing.
  • Platelet-rich fibrin (PRF) is a biomaterial used to promote tissue regeneration.

Purpose of the Study:

  • To evaluate the efficacy of a modified PRF formulation, Advanced PRF (A-PRF), in improving healing after impacted mandibular third molar extraction.
  • To compare A-PRF treatment with standard care (control) in terms of pain, swelling, soft tissue healing, trismus, and bone regeneration.

Main Methods:

  • Prospective study involving 20 patients with bilateral impacted mandibular third molars.
  • Surgical extraction performed in opposing quadrants at 3-4 week intervals.
  • One quadrant treated with A-PRF, the contralateral quadrant served as control.
  • Comparative assessment of pain, analgesic use, swelling, soft tissue healing, and trismus at 1, 3, and 7 days post-surgery.
  • Bone healing evaluated at 1, 3, and 6 months post-surgery.

Main Results:

  • A-PRF sites showed statistically significant improvements in pain (p=0.008), swelling (p=0.031), soft tissue healing (p=0.0001), and trismus (p=0.05) by the 3rd postoperative day compared to control sites.
  • Analgesic consumption was significantly reduced in A-PRF treated sites (p=0.004).
  • Bone healing was significantly enhanced in A-PRF sites at 1, 3, and 6 months post-surgery (p<0.05).

Conclusions:

  • Advanced PRF (A-PRF) demonstrates enhanced soft tissue and bone healing in extraction sockets.
  • A-PRF effectively reduces immediate postoperative symptoms such as pain, swelling, and trismus.
  • A-PRF offers a cost-effective method to improve patient comfort and surgical outcomes.