Related Experiment Video
Updated: Dec 22, 2025

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
Published on: October 4, 2024
A new era for nuclear medicine
1Interim Editor in Chief, Head of Nuclear Medicine and PET/CT Department Theagenio Cancer Hospital, Thessaloniki, Greece, hpavlidou@gmail.com.
Insights
The COVID-19 pandemic presents challenges for healthcare systems, including nuclear medicine departments. Implementing infection control measures and adapting clinical trial protocols are crucial for patient and staff safety during this global health crisis.
Area of Science:
- Nuclear Medicine
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic, caused by the novel coronavirus, has led to a global health crisis with significant impact on healthcare systems worldwide.
- Transmission occurs via respiratory droplets, bodily fluids, and contaminated surfaces, with potential for airborne spread in aerosol-generating procedures.
- Vulnerable populations, including the elderly and those with comorbidities, face higher risks of severe complications like acute respiratory distress syndrome (ARDS) and cytokine storm.
Discussion:
- Nuclear medicine departments must implement stringent infection control measures to prevent the spread of COVID-19 among patients and staff.
- Radiology and nuclear medicine preparedness are essential for maintaining diagnostic and interventional support during the pandemic.
- The International Atomic Energy Agency (IAEA) recommends postponing non-urgent nuclear medicine procedures following a risk assessment to minimize transmission.
Key Insights:
- An individualized approach to patient management in nuclear medicine is vital for controlling COVID-19 transmission.
- The pandemic has disrupted the supply chain for medical radioisotopes, impacting their availability for nuclear medicine procedures.
- The Hellenic Society of Nuclear Medicine (HSNM) and Hellenic Journal of Nuclear Medicine (HJNM) are adapting to new leadership and challenges during this era.
Outlook:
- Continued vigilance and adaptation of protocols are necessary for nuclear medicine departments to navigate the ongoing pandemic.
- Maintaining the scientific excellence and timely publication of research in nuclear medicine remains a priority.
- The HSNM and HJNM are committed to addressing future challenges in scientific and clinical nuclear medicine practice.
Abstract:
The coronavirus COVID-19 pandemic is the defining global health crisis of our time. Health care systems globally are amid an unprecedented challenge. Since its emergence in December 2019 in Wuhan, China, the virus has spread to 185 countries worldwide, with more than 2.63 million cases confirmed and more than 183 thousand related deaths (as of 23/04/2020). According to current evidence, the novel coronavirus is transmitted from human-to-human mainly via respiratory droplets of different sizes, contact with bodily fluids, or from contaminated surfaces. In the context of COVID-19, airborne transmission may be possible in specific circumstances and settings in which procedures that generate aerosols are performed. The common clinical symptoms of the highly pathogenic and large-scale epidemic virus include fever, cough, fatigue, ageusia and anosmia and in some patients, gastrointestinal infection symptoms. The elderly and patients with comorbidities are susceptible to infection and prone to severe complications, which may be associated with acute respiratory distress syndrome (ARDS) and cytokines storm. Currently, there are few specific antiviral strategies, but several potent candidates of antivirals and repurposed drugs are under urgent investigation. Under these circumstances, it is critical for health care settings, including nuclear medicine departments to take infection control measures, to prevent a potential spread not just among patients but also to staff members as well as to reconsider the performance of randomized clinical trials. There have already been papers on the radiology preparedness that should be applied to radiology and nuclear medicine departments to support the care of patients with COVID-19 and maintain radiologic diagnostic and interventional support for the entirety of the hospital and healthcare system, particularly for emergencies, without jeopardizing an outbreak in the units. Since most nuclear medicine diagnostic and therapeutic interventions are non-urgent, the general guidance from the International Atomic Energy Agency (IAEA) for infection prevention and control is to postpone scheduled procedure after cautious risk assessment, with certain exceptions. Individualized approach of each case is a sine qua non of ensuring low transmission of COVID-19 as well as effective and safe management of patients admitted to nuclear medicine departments. Another major issue raised is the possible impact COVID-19 on the transport of medical radioisotopes. By the 1st of April 2020, the Euratom Supply Agency (ESA) co-chaired the European Observatory on Supply of Medical Radioisotope expressing their concerns related to the impact of COVID-19 on the supply chain and inconsequence on the availability of the most vital medical radioisotopes used in nuclear medicine. Due to the current lockdown situation, extended border controls, reductions and elimination of many commercial passenger flights, competition and cost of cargo and charter options, required appropriate additional support. The new era of nuclear medicine practice worldwide coincides with a new era for the Hellenic Society of Nuclear Medicine (HSNM) and the Hellenic Journal of Nuclear Medicine (HJNM). The founder and Editor in Chief for more than 28 consecutive years, Professor Emeritus Philip Grammaticos, resigned leaving behind a benchmark for the presidencies and editors to come. His commitment to the conservation of a high level of scientific excellence of the published papers is the legacy which we wish to maintain in the future publications. The interim Editor in Chief of the current issue, would like to express her gratitude to Professor Emeritus Philip Grammaticos for his contribution to the global scientific community as well as to the incoming Editor in Chief Konstantinos Anagnostopoulos, MD, PhD, FRCP, FESC for accepting this new role. We wholeheartedly welcome the new Editor in Chief and the new members of the Editorial Board, wishing them an active, attentive and successful mandate. Hellenic Journal of Nuclear Medicine will remain true to the set principles, values and past and prepared to cope with future challenges in the scientific and clinical setting.
Related Concept Videos
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Nuclear Transmutation
Nuclear Magnetic Resonance (NMR): Overview
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
Isotopes and Radioisotopes
An isotope containing...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

