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Updated: Dec 22, 2025

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Multidetector computed tomography evaluation of synchronous lymphoma and other solid malignancies
Adel El-Badrawy1, Basma Gadelhak1, Eman M Helmy1
1Department of Radiology, Public Health and Community Medicine, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Multidetector computed tomography (MDCT) accurately identifies synchronous lymphoma and other solid malignancies. This imaging technique aids in understanding and potentially treating these co-occurring cancers.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Synchronous malignancies, including lymphoma and solid tumors, present diagnostic challenges.
- Accurate imaging is crucial for staging and treatment planning in patients with multiple cancers.
Purpose of the Study:
- To review multidetector computed tomography (MDCT) findings in patients with synchronous lymphoma and other solid malignancies.
- To evaluate the efficacy of MDCT in diagnosing co-occurring cancers.
Main Methods:
- Retrospective analysis of 18 patients diagnosed with lymphoma and other solid malignancies.
- MDCT scans were performed using 64-detector or 6-detector systems.
- All malignancies were pathologically confirmed.
Main Results:
- A total of 36 malignancies were identified across 18 patients.
- Lymphomas included Hodgkin disease (5 patients) and non-Hodgkin lymphoma (13 patients).
- Various solid malignancies were detected, including hepatocellular, bronchogenic, renal cell, breast, prostatic, gastric, endometrial, colonic, and thyroid carcinomas.
Conclusions:
- MDCT is an accurate imaging modality for evaluating synchronous lymphoma and solid malignancies.
- Further case accumulation may elucidate underlying mechanisms and inform new treatment strategies.
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