Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

79.3K
Overview
79.3K
CRISPR01:59

CRISPR

57.2K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
57.2K
CRISPR and crRNAs02:53

CRISPR and crRNAs

18.5K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
18.5K
Epigenetic Regulation01:46

Epigenetic Regulation

33.3K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
33.3K
Epigenetic Regulation01:37

Epigenetic Regulation

3.6K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
3.6K
RNA Editing02:23

RNA Editing

9.6K
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel Features and Considerations for ERA and Regulation of Crops Produced by Genome Editing.

Frontiers in bioengineering and biotechnology·2018
Same author

A research program for the socioeconomic impacts of gene editing regulation.

GM crops & food·2017
Same author

Regulatory framework for gene editing and other new breeding techniques (NBTs) in Argentina.

GM crops & food·2015
Same author

Proposed criteria for identifying GE crop plants that pose a low or negligible risk to the environment under conditions of low-level presence in seed.

Transgenic research·2015
Same author

Safety assessment of food products from r-DNA animals.

Comparative immunology, microbiology and infectious diseases·2008
Same author

Assessing local structural perturbations in proteins.

BMC bioinformatics·2005
Same journal

Discerning dangerous gain of function: most gain of function (GoF) research does not involve infectious microbes.

Frontiers in bioengineering and biotechnology·2026
Same journal

Microtopography screening to modulate the mitogenic effects of aqueous humor on human tenon fibroblasts.

Frontiers in bioengineering and biotechnology·2026
Same journal

Next-generation strategies for anterior cruciate ligament repair: constructing biointelligent ligament grafts integrating biomimetic design, immune modulation, and sensory feedback.

Frontiers in bioengineering and biotechnology·2026
Same journal

Collagen nanofiber reinforced alginate hydrogel tube microbioreactors for cell culture.

Frontiers in bioengineering and biotechnology·2026
Same journal

Calcium ions released from alginate hydrogel promote wound healing by enhancing fibroblast activity.

Frontiers in bioengineering and biotechnology·2026
Same journal

Application and validation of AI-assisted 3D-Printed gastroduodenal anatomical variation models in specialized nursing training.

Frontiers in bioengineering and biotechnology·2026
See all related articles

Related Experiment Video

Updated: Dec 22, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

35.2K

Gene Editing Regulation and Innovation Economics.

Agustina I Whelan1,2, Patricia Gutti1,3, Martin A Lema2,3

  • 1Maestría en Política y Gestión de la Ciencia y la Tecnología, Universidad de Buenos Aires, Buenos Aires, Argentina.

Frontiers in Bioengineering and Biotechnology
|May 5, 2020
PubMed
Summary
This summary is machine-generated.

Argentina

Keywords:
CRISPR-CASbioeconomybiotechnology indicatorsbiotechnology regulationgene editinggenome editinginnovation economynew breeding techniques

More Related Videos

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
09:43

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

Published on: January 3, 2025

3.1K
Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
07:17

Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

Published on: December 16, 2022

3.8K

Related Experiment Videos

Last Updated: Dec 22, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

35.2K
Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
09:43

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

Published on: January 3, 2025

3.1K
Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
07:17

Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

Published on: December 16, 2022

3.8K

Area of Science:

  • Agricultural Biotechnology
  • Regulatory Science
  • Innovation Economics

Background:

  • Argentina pioneered regulations for New Breeding Techniques (NBTs), distinguishing them from Genetically Modified Organisms (GMOs).
  • Four years of regulatory experience with NBTs, primarily gene-edited agricultural products, provide valuable insights.

Purpose of the Study:

  • To analyze the economic innovation impact of Argentina's regulatory framework for NBTs.
  • To compare the regulatory and market release trajectories of gene-edited products versus traditional GMOs.

Main Methods:

  • Comparative analysis of regulatory case data for NBT-derived products and deregulated GMOs in Argentina.
  • Assessment of development rates, developer diversity, and product profiles.

Main Results:

  • Gene-edited products exhibit faster "bench-to-market" timelines compared to early GMOs.
  • A broader range of developers, including SMEs and public institutions, are driving gene-editing innovation.
  • Product diversity in terms of traits and organisms is significantly higher for gene-edited products.

Conclusions:

  • Argentina's regulatory approach facilitates distinct innovation pathways for gene editing.
  • NBTs, particularly gene editing, offer diverse and accelerated innovation opportunities for agriculture.
  • Findings have significant implications for agricultural and biotechnology sectors, especially in developing nations.