Typical radiological progression and clinical features of patients with coronavirus disease 2019

Min Wang1, Linghong Guo1, Qi Chen1

  • 1Department of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.

Aging
|May 5, 2020
PubMed

Insights

The study identified typical radiological features of Coronavirus disease 2019 (COVID-19) using chest CT scans. Key findings include scattered bilateral ground-glass opacities, fever, and cough, aiding early diagnosis and progression assessment.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19) is a global health concern.
  • Understanding its radiological manifestations is crucial for diagnosis and management.

Purpose of the Study:

  • To describe the typical radiological features and progression of COVID-19 patients.
  • To correlate imaging findings with clinical and laboratory data.

Main Methods:

  • Retrospective review of chest CT scans, laboratory findings, and clinical records.
  • Analysis of 66 COVID-19 patients admitted between January 21 and February 2, 2020.
  • Evaluation of lesion characteristics, lobe involvement, and comorbid conditions.

Main Results:

  • Predominant symptoms included fever (91%) and cough (56%).
  • Typical CT findings were scattered, bilateral ground-glass opacities (97%) with air bronchogram sign (71%).
  • More than two lobes were involved in 73% of patients, with lower lobes most affected.

Conclusions:

  • Typical radiological features of COVID-19 include scattered ground-glass opacities in bilateral lobes.
  • Fever and cough are major clinical symptoms.
  • Integrating chest CT, clinical symptoms, and lab results aids early COVID-19 diagnosis and progression monitoring.

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