COVID-19 pneumonia in kidney transplant recipients-Where we are?

David José de Barros Machado1,2, Luiz Estevam Ianhez1

  • 1Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.

Insights

The first COVID-19 case in a Brazilian transplant patient involved SARS-CoV-2 pneumonia. A multimodal strategy including supportive care, reduced immunosuppression, antiviral drugs, and heparin led to recovery and discharge.

Area of Science:

  • * Infectious Diseases
  • * Transplant Surgery
  • * Critical Care Medicine

Background:

  • * The emergence of SARS-CoV-2 (novel coronavirus) in late 2019 led to the COVID-19 pandemic.
  • * Brazil reported its first COVID-19 case on March 20, 2020.
  • * Transplant recipients are considered a vulnerable population during infectious disease outbreaks due to their immunosuppressed status.

Observation:

  • * This report details the first case of COVID-19 in a liver and kidney transplant recipient in Brazil.
  • * The patient presented with SARS-CoV-2 pneumonia but without respiratory failure.
  • * The case occurred in the context of the early stages of the COVID-19 pandemic in Brazil.

Findings:

  • * A clinical multimodal strategy was employed, including symptomatic support, reduced immunosuppression, anti-coronavirus drugs, and heparin.
  • * The patient exhibited progressive improvement in symptoms.
  • * The patient was successfully discharged from the hospital.

Implications:

  • * This case highlights the importance of early diagnosis and tailored management strategies for transplant recipients with COVID-19.
  • * The multimodal approach demonstrated potential efficacy in managing SARS-CoV-2 pneumonia in this high-risk group.
  • * Further research is warranted to establish optimal treatment protocols for transplant patients infected with SARS-CoV-2.

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