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Updated: Dec 22, 2025

Murine Kidney Transplant Technique
Published on: October 20, 2015
COVID-19 pneumonia in kidney transplant recipients-Where we are?
David José de Barros Machado1,2, Luiz Estevam Ianhez1
1Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.
Insights
The first COVID-19 case in a Brazilian transplant patient involved SARS-CoV-2 pneumonia. A multimodal strategy including supportive care, reduced immunosuppression, antiviral drugs, and heparin led to recovery and discharge.
Area of Science:
- * Infectious Diseases
- * Transplant Surgery
- * Critical Care Medicine
Background:
- * The emergence of SARS-CoV-2 (novel coronavirus) in late 2019 led to the COVID-19 pandemic.
- * Brazil reported its first COVID-19 case on March 20, 2020.
- * Transplant recipients are considered a vulnerable population during infectious disease outbreaks due to their immunosuppressed status.
Observation:
- * This report details the first case of COVID-19 in a liver and kidney transplant recipient in Brazil.
- * The patient presented with SARS-CoV-2 pneumonia but without respiratory failure.
- * The case occurred in the context of the early stages of the COVID-19 pandemic in Brazil.
Findings:
- * A clinical multimodal strategy was employed, including symptomatic support, reduced immunosuppression, anti-coronavirus drugs, and heparin.
- * The patient exhibited progressive improvement in symptoms.
- * The patient was successfully discharged from the hospital.
Implications:
- * This case highlights the importance of early diagnosis and tailored management strategies for transplant recipients with COVID-19.
- * The multimodal approach demonstrated potential efficacy in managing SARS-CoV-2 pneumonia in this high-risk group.
- * Further research is warranted to establish optimal treatment protocols for transplant patients infected with SARS-CoV-2.
Abstract:
In late December 2019, China reported cases of respiratory illness in humans that involved a novel coronavirus SARS-CoV-2. On March 20, 2020, the first coronavirus disease 2019 (COVID-19) in Brazil was diagnosed, and by now, we present the report on the first case of COVID among transplant recipients in our country. A liver and kidney transplant patient with SARS-CoV-2 pneumonia without respiratory failure was treated in a clinical multimodal strategy consisting of symptomatic support therapy, immunosuppression reduction, use of anti-coronavirus drugs and heparin leading to a progressive improvement of patient symptoms till discharge. The authors also present a comprehensive review of published cases.
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Kidney Transplant I: Introduction
Kidney Transplant III: Nursing Management
Kidney Transplant II: Surgical Procedure
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury II: Pathophysiology

